New PDF release: CrushThe Boards - Ultimate USMLE Step 2 Review

By ed A. Brochert

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Classic sitcs ofinvolvemmt arc in t h e pelvis an d skull. Watch for a persm who has lidd 10 buy larger-size hats. Patients may complain of hone pain, osteoarthritis, nerve dcafncss, or paraplegia. Tlie risk r 1 1 osteosarconia is increased in affected hones. Treat with NSAIDs, possibly eiidlrniate or calcitoiiin for sewre discasr. Note: With jiivenile RA, rlreiirriatoid factor is oftcn negative. S y ~ n p t i ~ r i i s include fatigttc, dyspnca mi pxwtion, liglit-beadedncss, dizziness. , jamidice in liciiiolytic anemia, positive srool guaiac in GI bleed).

Tlironi hotic thr~i~nliocytojieiiic j i ~ ~ r ] > i i ar ai i,d llcinolytic iireiiiic syndrmnc (look tiir scliiscocytes/KHC Crag riieiits and appropriate otlier fiiidiiigs); oilier hein~~glohiiiopattries (lieiiiogld>ins C a i d 1: fairly c o n ~ i i i o n;) paroxysirial iioctrirnal o r wld licnii,glohiiiiiria; Clor~riitiurnperfringens, malaria, habesiosis, aiid Irypcrsplenism (always accoriipaiiied by splc~iomegalyarid &en by low platelcts aiid white blood cells) Transfusions: always bascd on cliriical groiiiids.

Clotting tests: PT for extrinsic system (prolonged hy warfarin), 1'TT for intrinsic system (pro Iongcd hy heparin), and BT for platrlet lirnctiori: ' ~ l i r o n i h o c y t o ~ ~ rmay ~ i i a he caused hy idiopatliic tl~ror~tl~ocyt~ipcniic piirpriia, thro~rrbotic nrernic syndrome, disseminakd intravascular coagulation, tliroin hocytopcnic purpura, lii~ni~ilytic Hematology 57 HIV, splenic sequestration, 11eparii1 (treat b y f i r s t stopping licpariii), other medications (especially quinidine and snlla drugs), autoimmune disease, and alcohol.

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CrushThe Boards - Ultimate USMLE Step 2 Review by ed A. Brochert

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