By Cecelia Hutto, Gwendolyn B. Scott
A unusual panel of pediatric and infectious affliction experts found in an simply obtainable layout all of the details had to diagnose a wide selection of infections in either the pregnant girl and the neonate. geared up by way of particular an infection or comparable infections, the publication presents pertinent information regarding the epidemiology of every an infection within the pregnant girl and her neonate, in addition to the chance of transmission to the fetus or neonate, the spectrum of medical affliction, and a prompt method of the analysis of the an infection in either the mummy and neonate. The emphasis is on realizing what assessments to reserve and the way to interpret the consequences, with the method of prognosis in every one bankruptcy encompassing, not just the pregnant lady, but additionally her neonate. The ebook covers quite a lot of microorganisms which are either universal and unusual reasons of congenital and perinatal infections, together with the herpes simplex virus, HIV, toxoplasmosis, syphilis, CMV, tuberculosis, malaria, dengue, lymphocytic choriomeningtis virus, and parvovirus.
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Extra resources for Congenital and Perinatal Infections (Infectious Disease)
13. Rotbart HA. Enzymatic RNA amplification of the enteroviruses. J Clin Microbiol 1990;28:438–442. 14. Kilpatrick DR, Nottay B, Yang C, et al. Group-specific identification of polioviruses by PCR using primers containing mixed-base or deoxyinosine residues at positions of codon degeneracy. J Clin Microbiol 1996;34:2990–2996. 15. Forghani B, Erdman DD. Amplification and detection of viral nucleic acids. In: Lennette EH, Lennette DA, Lennette ET, eds. Diagnostic Procedures for Viral, Rickettsial and Chlamydial Infections, 7th ed.
PCR has not been fully standardized, so many laboratories have in-house procedures. Without standardized tests, it is difficult to compare results between laboratories. Also, PCR is subject to contamination, resulting in false-positive results and inhibition of the reaction, resulting in false negatives. Interpretation The significance of a positive result for direct detection of an agent depends on the sensitivity and specificity of the test, the relationship of the agent with the syndrome or disease in question, and the site from which the specimen was obtained.
Clin Microbiol Rev 2002;5:66–78. 15. Cleary T, Roudel G, Casillas O, Miller N. Rapid and specific detection of Mycobacterium tuberculosis using the Smart-Cycler instrument and a fluorogenic probe. J Clin Microbiol 2003;41:4783–4786. Viral Infection Diagnosis 23 3 Diagnosis of Viral Infections by Viral Isolation and Identification or by Direct Detection David Schnurr INTRODUCTION Laboratory diagnostic tests for viral infections play an important role in the management of infections during pregnancy and in the newborn infant.
Congenital and Perinatal Infections (Infectious Disease) by Cecelia Hutto, Gwendolyn B. Scott